Ins2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8161916
Gene symbol:	Ins2
Gene name:	insulin II

Antibody:	anti-insulin
Detection system:	Secondary antibody coupled to Cy2
Assay notes:	The specificity of the antibody used was not detailed; both family members have been annotated.

Results

4A ©

Specimen 4A: postnatal day 0 (more

)
Note: Double labeled: green - Ins2 and Ins1; red - Sst (assay MGI:8161642).

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Present		4A

4B ©

Specimen 4B: postnatal day 0; Arx^tm1Gldn/?, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male. Double labeled: green - Ins2 and Ins1; red - Sst (assay MGI:8161642).

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Present		4B

4C ©

Specimen 4C: postnatal day 0; Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr (more

)
Note: Double labeled: green - Ins2 and Ins1; red - Sst (assay MGI:8161642).

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Absent		4C

4D ©

Specimen 4D: postnatal day 0; Arx^tm1Gldn/?, Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male. Double labeled: green - Ins2 and Ins1; red - Sst (assay MGI:8161642).

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Absent		4D

S4E ©

Specimen S4E: postnatal day 0 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Present		S4E

S4F ©

Specimen S4F: postnatal day 0; Arx^tm1Gldn/?, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Present		S4F

S4G ©

Specimen S4G: postnatal day 0; Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Absent		S4G

S4H ©

Specimen S4H: postnatal day 0; Arx^tm1Gldn/?, Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	type B pancreatic cell	Absent		S4H

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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