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Gene Expression Data
Assay Details
Assay
Reference: J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8161666
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Detection system: Secondary antibody coupled to Cy2
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 4A: postnatal day 0 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:8161642).
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Present 4A
Specimen 4B: postnatal day 0; Arxtm1Gldn/?, Tg(Pdx1-cre)6Tuv/0 (more )
Note: Conditional mutant. Arxtm1Gldn/Arxtm1Gldn in female, Arxtm1Gldn/Y in male. Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:8161642).
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Present 4B
Specimen 4C: postnatal day 0; Nkx2-2tm1Jlr/Nkx2-2tm1Jlr (more )
Note: Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:8161642).
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Absent 4C
Specimen 4D: postnatal day 0; Arxtm1Gldn/?, Nkx2-2tm1Jlr/Nkx2-2tm1Jlr, Tg(Pdx1-cre)6Tuv/0 (more )
Note: Conditional mutant. Arxtm1Gldn/Arxtm1Gldn in female, Arxtm1Gldn/Y in male. Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:8161642).
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Absent 4D
Specimen S4E: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Present S4E
Specimen S4F: postnatal day 0; Arxtm1Gldn/?, Tg(Neurog3-cre)C1Able/0 (more )
Note: Conditional mutant. Arxtm1Gldn/Arxtm1Gldn in female, Arxtm1Gldn/Y in male.
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Present S4F
Specimen S4G: postnatal day 0; Nkx2-2tm1Jlr/Nkx2-2tm1Jlr (more )
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Absent S4G
Specimen S4H: postnatal day 0; Arxtm1Gldn/?, Nkx2-2tm1Jlr/Nkx2-2tm1Jlr, Tg(Neurog3-cre)C1Able/0 (more )
Note: Conditional mutant. Arxtm1Gldn/Arxtm1Gldn in female, Arxtm1Gldn/Y in male.
Structure Cell Type Level Pattern Image Note
TS27: pancreas type B pancreatic cell Absent S4H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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