About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:275567 Zurkirchen L, et al., Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019 May 16;10(1):2192
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7856690
Gene symbol: Dcx
Gene name: doublecortin
Antibody: Anti-Doublecortin (AB2253)
Detection system: Secondary antibody
Results
Specimen S1c E10.5 Dcx: embryonic day 10.5 (more )
Note: Double labeled: gray - Dcx; green - Sox2 (assay MGI:7856689).
Structure Cell Type Level Pattern Image Note
TS17: telencephalon neuron Present S1c E10.5 Sox2 Dcx inset , S1c E10.5 Sox2 Dcx Expression in immature neurons.
Specimen S1c E12.5 Dcx: embryonic day 12.5 (more )
Note: Double labeled: gray - Dcx; green - Sox2 (assay MGI:7856689).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex neuron Present S1c E12.5 Sox2 Dcx , S1c E12.5 Sox2 Dcx inset Expression in immature neurons.
Specimen S1c E18.5 Dcx: embryonic day 18.5 (more )
Note: Double labeled: gray - Dcx; green - Sox2 (assay MGI:7856689).
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex neuron Present S1c E18.5 Sox2 Dcx , S1c E18.5 Sox2 Dcx inset upper
Specimen S2a Control Dcx: embryonic day 12.5 (more )
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt. Double labeled: red - Dcx; green - Sox2 (assay MGI:7856689).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex neuron Present S2a Control Expression in immature neurons.
Specimen S2a Yy1cKO Dcx: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: red - Dcx; green - Sox2 (assay MGI:7856689).
Structure Level Pattern Image Note
TS20: cerebral cortex Weak S2a Yy1cKO Number of expressing cells decreased compared to control, but relative abundance of Dcx-expressing to Sox2-expressing cells was not changed.
Specimen 3a Control Dcx: embryonic day 12.5 (more )
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt. Double labeled: blue - Dcx; red - Trp53 (assay MGI:7856702).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3a Control
Specimen 3a Yy1cKO Dcx: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: blue - Dcx; red - Trp53 (assay MGI:7856702).
Structure Level Pattern Image Note
TS20: cerebral cortex Weak 3a Yy1cKO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory