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Gene Expression Data
Assay Details
Assay
Reference: J:275567 Zurkirchen L, et al., Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019 May 16;10(1):2192
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7856688
Gene symbol: Yy1
Gene name: YY1 transcription factor
Antibody: anti-YY1 (H-414; sc-1703)
Detection system: Secondary antibody
Assay notes: Two Yy1 antibodies were described, but the one used in this assay was not detailed. Anti-Yy1 (sc-7341) MGI:7580449 may have been used in this assay.
Results
Specimen S1c E10.5 Yy1: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: telencephalon neural progenitor cell Present S1c E10.5 Yy1 inset , S1c E10.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
TS17: telencephalon neuron Present S1c E10.5 Yy1 inset , S1c E10.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
Specimen S1c E12.5 Yy1: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex neural progenitor cell Present S1c E12.5 Yy1 inset , S1c E12.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
TS20: cerebral cortex neuron Present S1c E12.5 Yy1 inset , S1c E12.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
Specimen S1c E18.5 Yy1: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex neural progenitor cell Present S1c E18.5 Yy1 inset lower , S1c E18.5 Yy1 inset upper , S1c E18.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
TS26: cerebral cortex neuron Present S1c E18.5 Yy1 inset lower , S1c E18.5 Yy1 inset upper , S1c E18.5 Yy1 Expression in Sox2-expressing neural progenitor cells and Dcx-expressing immature neurons.
Specimen S1d E10.5 Control: embryonic day 10.5 (more )
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt.
Structure Level Pattern Image Note
TS17: telencephalon Present S1d E10.5 Control
Specimen S1d E10.5 Yy1cKO: embryonic day 10.5; Emx1tm1(cre)Krj/Emx1+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Weak S1d E10.5 Yy1cKO Expression lost in single cells from E10.5 onwards.
Specimen S1d E11.5 Control: embryonic day 11.5 (more )
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt.
Structure Level Pattern Image Note
TS19: telencephalon Present S1d E11.5 Control
Specimen S1d E11.5 Yy1cKO: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Absent S1d E11.5 Yy1cKO Expression completely lost in all cells of dorsal cortex by E11.5
Specimen S1d E12.5 Control: embryonic day 12.5 (more )
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt.
Structure Level Pattern Image Note
TS20: cerebral cortex Present S1d E12.5 Control
Specimen S1d E12.5 Yy1cKO: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebral cortex Absent S1d E12.5 Yy1cKO
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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