About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:161201 Gao N, et al., Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855374
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1
Detection system: Secondary antibody
Assay notes: Control embryos were derived from matings between Cdx2loxP/+ VillinCre+ male mice and Cdx2loxP/loxP female mice.
Results
Specimen 1J ZO-1: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: red - Tjp1; green - Cdh1 (assay MGI:7855370).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1J , 1J inset Expression localized at apical end of Cdh1-expressing domain.
Specimen 1K ZO-1: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: red - Tjp1; green - Cdh1 (assay MGI:7855370).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1K , 1K inset Expanded expression, with reticular pattern in outer layers of multilayered epithelium.
Specimen S5c/e ZO-1: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: red - Tjp1; green - Cdh1 (assay MGI:7855370).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S5e , S5c Co-localization with Cdh1 expression
Specimen S5d/f ZO-1: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: red - Tjp1; green - Cdh1 (assay MGI:7855370).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S5d , S5f Co-localization with Cdh1 expression
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory