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Gene Expression Data
Assay Details
Assay
Reference: J:161201 Gao N, et al., Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855370
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin
Detection system: Secondary antibody
Assay notes: Control embryos were derived from matings between Cdx2loxP/+ VillinCre+ male mice and Cdx2loxP/loxP female mice.
Results
Specimen 1H Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - DBA lectin.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1H Expression in basolateral membrane, excluded from apical surface in normal intestinal epithelial cells.
Specimen 1I Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - DBA lectin.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1I Expression ectopically localized to entire cellular membrane.
Specimen 1J Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:7855374).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1J , 1J inset Expression in basolateral membrane, excluded from apical surface in normal intestinal epithelial cells.
Specimen 1K Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:7855374).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1K , 1K inset Expression ectopically localized to entire cellular membrane.
Specimen 1L Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - laminin.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1L Expression in basolateral membrane, excluded from apical surface in normal intestinal epithelial cells.
Specimen 1M Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - laminin.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 1M Expression ectopically localized to entire cellular membrane.
Specimen S2a: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - DNA.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S2a Expression in basolateral membrane, excluded from apical surface in normal intestinal epithelial cells.
Specimen S2b: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - DNA.
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S2b Expression ectopically localized to entire cellular membrane.
Specimen S5a/e Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:7855374).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S5a , S5e Expression colocalized with Tjp1.
Specimen S5b/f Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Tjp1 (assay MGI:7855374).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted S5b , S5f Expression colocalized with Tjp1.
Specimen 4C Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Prkcz (assay MGI:7855376).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 4C Expression colocalized with Prkcz.
Specimen 4D Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Prkcz (assay MGI:7855376).
Structure Level Pattern Image Note
TS26: intestine epithelium Present Regionally restricted 4D Expression colocalized with Prkcz.
Specimen S12a Ecad: embryonic day 15.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS23: intestine Present S12a merged
Specimen S12b Ecad: embryonic day 15.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS23: intestine Present S12b merged
Specimen S12c Ecad: embryonic day 15.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS23: intestine Present S12c merged
Specimen S12d Ecad: embryonic day 15.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS23: intestine Present S12d merged
Specimen 5E Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5E Expression in basolateral plasma membranes.
Specimen 5F Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Lamp1 (assay MGI:7855378).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5F Expression in basolateral plasma membranes.
Specimen 5G Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Eea1 (assay MGI:7855383).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5G Expression in basolateral plasma membranes.
Specimen 5H Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Eea1 (assay MGI:7855383).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5H Expression in basolateral plasma membranes.
Specimen 5I Ecad: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Map1lc3a (assay MGI:7855384) and Map1lc3b (assay MGI:7855386).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5I Expression in basolateral plasma membranes.
Specimen 5J Ecad: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Map1lc3a (assay MGI:7855384) and Map1lc3b (assay MGI:7855386).
Structure Level Pattern Image Note
TS26: intestine Present Regionally restricted 5J Expression in basolateral plasma membranes.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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