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Gene Expression Data
Assay Details
Assay
Reference: J:171421 Vandunk C, et al., Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
Assay type: RNA in situ
MGI Accession ID: MGI:7661038
Gene symbol: Fzd5
Gene name: frizzled class receptor 5
Probe: IMAGE clone 445088
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Two possible probes were referenced: MGI:270424 and MGI:7660796. The probe used in this assay was not specified.
Results
Specimen 6C E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon floor plate Present Regionally restricted 6C E10.5 Fzd5 Expression was detected in a region surrounding the base of the third ventricle.
Specimen 6C E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6C E11.5 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the dorsoventral dimension.
Specimen 6C E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon floor plate Present Regionally restricted 6C E12.5 Fzd5 At E12.5, expression was still present beneath the third ventricle but was restricted to the dorsal region overlapping with the Six3/Six6 region only.
Specimen 6C E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon floor plate Present Regionally restricted 6C E13.5 Fzd5 At E13.5, expression was still present beneath the third ventricle but was restricted to the dorsal region overlapping with the Six3/Six6 region only.
Specimen 6D E11.5 Rostral 1: embryonic day 11.5 (more )
Note: Rostral-most section of a rostral-caudal series beginning from rostral eye fields level.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 Rostral 1 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 2: embryonic day 11.5 (more )
Note: Second section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 2 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 3: embryonic day 11.5 (more )
Note: Third section of a rostral-caudal series.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 3 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 4: embryonic day 11.5 (more )
Note: Fourth section of a rostral-caudal series.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 4 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 Caudal 5: embryonic day 11.5 (more )
Note: Caudal-most section of a rostral-caudal series ending at developing pituitary.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 Caudal 5 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E13.5 Rostral 1: embryonic day 13.5 (more )
Note: Rostral-most section of a rostral-caudal series beginning from rostral eye fields level.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 Rostral 1 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 2: embryonic day 13.5 (more )
Note: Second section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 2 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 3: embryonic day 13.5 (more )
Note: Third section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 3 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 4: embryonic day 13.5 (more )
Note: Fourth section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 4 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 Caudal 5: embryonic day 13.5 (more )
Note: Caudal-most section of a rostral-caudal series ending at developing pituitary.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 Caudal 5 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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