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Gene Expression Data
Assay Details
Assay
Reference: J:154534 Martinez G, et al., Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4794-806
Assay type: RT-PCR
MGI Accession ID: MGI:7659089
Gene symbol: Fzd5
Gene name: frizzled class receptor 5
Probe: Fzd5-pF, Fzd5-pR
Probe preparation: labelled with SYBR green
Assay notes: Table 1. Quantitative RT-PCR. Relative expression was normalized to five housekeeping genes.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex Note
WT E14.5 TS22: lens Present 1 µg; total RNA involves: FVB/N Tg(Cryaa-cre)10Mlr/0Not Specified
APC10 E14.5 TS22: lens Present (b) 1 µg; total RNA involves: 129S4/SvJae * FVB/N Apctm1Tno/Apctm1Tno, Tg(Cryaa-cre)10Mlr/0Not Specified Conditional mutant.
BetaCatEx310 E14.5 TS22: lens Present (c) 1 µg; total RNA involves: 129X1/SvJ * FVB/N Ctnnb1tm1Mmt/Ctnnb1tm1Mmt, Tg(Cryaa-cre)10Mlr/0Not Specified Conditional mutant.
Notes:
(a) The mutants showed discordant expression patterns, being significantly upregulated in one and significantly downregulated in the other.
(b) Observed -1.5 fold change compared with wild type.
(c) Observed 5.7 fold change compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory