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Gene Expression Data
Assay Details
Assay
Reference: J:211641 Bhansali P, et al., Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice. Neural Dev. 2014;9:11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645877
Gene symbol: Zic2
Gene name: zinc finger protein of the cerebellum 2
Antibody: anti-Zic2
Results
Specimen 1B Pigmented: embryonic day 15.5; Tyrc-2J/Tyr+ (more )
Note: Retinal flat mount.
Structure Cell Type Level Pattern Image Note
TS23: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 1B Pigmented Expression is in retinal ganglion cells in the ventrotemporal retina.
TS23: eye anterior segment Present Regionally restricted 1B Pigmented Expression is in the ciliary marginal zone.

Specimen 1B Albino: embryonic day 15.5; Tyrc-2J/Tyrc-2J (more )
Note: Retinal flat mount.
Structure Cell Type Level Pattern Image Note
TS23: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 1B Albino Expression in this mutant is similar to pigmented retinas but the density of expressing cells is reduced.

Specimen 2A Pigmented: embryonic day 15.5; Tyrc-2J/Tyr+ (more )
Note: Double labeled: red - Zic2; green - Isl1 (assay MGI:7645878) and Isl2 (assay MGI:7645880).
Structure Cell Type Level Pattern Image Note
TS23: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 2A Pigmented Zic2 , 2A Pigmented merged Expression is in retinal ganglion cells in the most peripheral region of the ventrotemporal retina.

Specimen 2A Albino: embryonic day 15.5; Tyrc-2J/Tyrc-2J (more )
Note: Double labeled: red - Zic2; green - Isl1 (assay MGI:7645878) and Isl2 (assay MGI:7645880).
Structure Cell Type Level Pattern Image Note
TS23: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 2A Albino Zic2 , 2A Albino Merged Expression in this mutant is similar to pigmented retinas but the number of expressing cells is reduced.

Specimen 3A Pigmented: embryonic day 17.5; Tyrc-2J/Tyr+ (more )
Note: Double labeled: red - Zic2; green - Isl1 (assay MGI:7645878) and Isl2 (assay MGI:7645880).
Structure Cell Type Level Pattern Image Note
TS25: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 3A Pigmented Expression is in retinal ganglion cells in the ventrotemporal retina.

Specimen 3A Albino: embryonic day 17.5; Tyrc-2J/Tyrc-2J (more )
Note: Double labeled: red - Zic2; green - Isl1 (assay MGI:7645878) and Isl2 (assay MGI:7645880).
Structure Cell Type Level Pattern Image Note
TS25: retina ganglion cell layer retinal ganglion cell Present Regionally restricted 3A Albino Expression in this mutant is similar to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory