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Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: RNA in situ
MGI Accession ID: MGI:7643718
Gene symbol: Sema3c
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Probe: Sema3c probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S6A: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6A Expression was detected in post-migratory cardiac neural crest cells.
TS19: cardiac muscle tissue Present S6A

Specimen S6B: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Absent S6B
TS19: cardiac muscle tissue Present S6B Myocardial expression was not affected in the mutant.

Specimen S6C: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6C Expression was detected in post-migratory cardiac neural crest cells.
TS19: cardiac muscle tissue Present S6C

Specimen S6D: embryonic day 11.5; Twist1tm1Bhr/Twist1tm2Bhr, Hand1tm1.1(EGFP/cre)Abfi/Hand1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6D Expression was detected in post-migratory cardiac neural crest cells and was indistinguishable from control.
TS19: cardiac muscle tissue Present S6D

Specimen S6E: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6E Expression was detected in post-migratory cardiac neural crest cells.

Specimen S6F: embryonic day 11.5; Twist1Ska10/Twist1+ (more )
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6F Expression was detected in post-migratory cardiac neural crest cells and was indistinguishable from control.

Specimen S6G: embryonic day 11.5; Twist1Ska10/Twist1Ska10 (more )
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endocardial cushion neural crest cell Present Regionally restricted S6G Expression was detected in post-migratory cardiac neural crest cells and was indistinguishable from control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory