About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:35877 Xiang M, et al., Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11950-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7641436
Gene symbol: Pou4f3
Gene name: POU domain, class 4, transcription factor 3
Antibody: anti-Brn-3c
Results
Specimen 3E: embryonic day 20.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: dorsal root ganglion neuron Present 3E Expression in a minority of neurons.
Specimen 3F: embryonic day 20.0; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Cell Type Level Pattern Image Note
TS26: dorsal root ganglion neuron Trace 3F Number of expressing cells greatly reduced (5- to 10-fold) compared to wild type.
Specimen 4K: embryonic day 20.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: trigeminal ganglion neuron Present 4K Expression in a minority of neurons.
Specimen 4L: embryonic day 20.0; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Cell Type Level Pattern Image Note
TS26: trigeminal ganglion neuron Trace 4L Density of expressing cells reduced ~5-fold compared to wild type.
Specimen +/+ not shown: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: retina ganglion cell layer Present
Specimen -/- not shown: embryonic day 20.0; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS26: retina ganglion cell layer Present Expression unaffected compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory