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Gene Expression Data
Assay Details
Assay
Reference: J:317091 Nakajima K, et al., Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier's disease, causes behavioral abnormalities and a hyper-dopaminergic state. Hum Mol Genet. 2021 Aug 28;30(18):1762-1772
Assay type: Western blot
MGI Accession ID: MGI:7610265
Gene symbol: Atp2a2
Gene name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Antibody: anti-SERCA2 (C-20): sc-8094
Assay notes: Another antibody (MGI:7610192) could be used too.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
Control P m 3-4 TS28: brain Present involves: C57BL/6 * SJL Tg(Nes-cre)1Kln/0Male
Control P m 3-4 TS28: brain Present involves: C57BL/6 * SJL Tg(Nes-cre)1Kln/0Male
hetero cKO P m 3-4 TS28: brain Present (a) involves: C57BL/6 * SJL Atp2a2tm1c(EUCOMM)Hmgu/Atp2a2+, Tg(Nes-cre)1Kln/0Male Conditional mutant.
hetero cKO P m 3-4 TS28: brain Present (a) involves: C57BL/6 * SJL Atp2a2tm1c(EUCOMM)Hmgu/Atp2a2+, Tg(Nes-cre)1Kln/0Male Conditional mutant.
Notes:
(a) Approximately half that of control mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory