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Gene Expression Data
Assay Details
Assay
Reference: J:95889 Wines-Samuelson M, et al., Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol. 2005 Jan 15;277(2):332-46
Assay type: Western blot
MGI Accession ID: MGI:7571576
Gene symbol: Nes
Gene name: nestin
Antibody: clone RC2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure 200 kDa (a) Genetic BackgroundMutant Allele(s)Sex Note
E12.5 ctrl E12.5 TS20: brain Present involves: 129S4/SvJae Psen1tm2Shn/Psen1+Not Specified
E12.5 cKO E12.5 TS20: brain Present involves: 129S4/SvJae * C57BL/6 * SJL Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
E12.5 ctrl E12.5 TS20: brain Present involves: 129S4/SvJae Psen1tm2Shn/Psen1+Not Specified
E12.5 cKO E12.5 TS20: brain Present involves: 129S4/SvJae * C57BL/6 * SJL Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
E17.5 ctrl E17.5 TS25: brain Present involves: 129S4/SvJae Psen1tm2Shn/Psen1+Not Specified
E17.5 cKO E17.5 TS25: brain Weak involves: 129S4/SvJae * C57BL/6 * SJL Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
E17.5 ctrl E17.5 TS25: brain Present involves: 129S4/SvJae Psen1tm2Shn/Psen1+Not Specified
E17.5 cKO E17.5 TS25: brain Weak involves: 129S4/SvJae * C57BL/6 * SJL Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
Notes:
(a) Expression levels were slightly reduced in mutants versus controls at E12.5 (92%) and diminish to 54% of control levels at E17.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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