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Gene Expression Data
Assay Details
Assay
Reference: J:95889 Wines-Samuelson M, et al., Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol. 2005 Jan 15;277(2):332-46
Assay type: RNA in situ
MGI Accession ID: MGI:7571567
Gene symbol: Psen1
Gene name: presenilin 1
Probe: PS1 probe
Probe preparation: Antisense labelled with radioactivity RNA
Results
Specimen 1A E9.5 Control: embryonic day 9.5; Psen1tm2Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS15: future brain Present 1A E9.5 Control

Specimen 1A E9.5 PS1 cKO: embryonic day 9.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: future brain Present 1A E9.5 PS1 cKO

Specimen 1A E10.5 Control: embryonic day 10.5; Psen1tm2Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1A E10.5 Control

Specimen 1A E10.5 PS1 cKO: embryonic day 10.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain Present 1A E10.5 PS1 cKO A slight reduction of expression was detected in the conditional knockout brain at E10.5.

Specimen 1A E11.5 Control: embryonic day 11.5; Psen1tm2Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS19: brain Present 1A E11.5 Control

Specimen 1A E11.5 PS1 cKO: embryonic day 11.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: brain Weak 1A E11.5 PS1 cKO

Specimen 1A E12.5 Control: embryonic day 12.5; Psen1tm2Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS20: brain Present 1A E12.5 Control

Specimen 1A E12.5 PS1 cKO: embryonic day 12.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: brain Absent 1A E12.5 PS1 cKO

Specimen 1A E15.5 Control: embryonic day 15.5; Psen1tm2Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS23: brain Present 1A E15.5 Control

Specimen 1A E15.5 PS1 cKO: embryonic day 15.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: brain Absent 1A E15.5 PS1 cKO


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory