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Gene Expression Data
Assay Details
Assay
Reference: J:233705 Zhao H, et al., Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. J Biol Chem. 2016 May 6;291(19):10201-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7562536
Gene symbol: Pcna
Gene name: proliferating cell nuclear antigen
Antibody: PC10
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 5G upper: embryonic day 13.5; Rb1tm3Tyj/Rb1tm3Tyj, Skp2tm1Kin/Skp2tm1Kin, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Pcna; green - TUNEL.
Structure Level Pattern Image Note
TS21: brain Present 5G PCNA upper , 5G merge upper Coexpressed in TUNEL+ cells.
Specimen 5G lower: embryonic day 13.5; Rb1tm3Tyj/Rb1tm3Tyj, Skp2tm1Kin/Skp2tm1Kin, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Pcna; green - Casp3 (assay MGI:7562537).
Structure Level Pattern Image Note
TS21: brain Present 5G merge lower , 5G PCNA lower Coexpressed with Casp3.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory