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Gene Expression Data
Assay Details
Assay
Reference: J:205196 Shetty AS, et al., Lhx2 regulates a cortex-specific mechanism for barrel formation. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4913-21
Assay type: RNA in situ
MGI Accession ID: MGI:7543270
Gene symbol: Lhx2
Gene name: LIM homeobox protein 2
Probe: Lhx2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 9.5; Emx1tm1(cre)Krj/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: telencephalon Strong 1A Strong expression was seen in dorsal telencephalon.
Specimen 1B: embryonic day 10.0; Emx1tm1(cre)Krj/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: telencephalon Present 1B A dramatic decline in expression in the dorsal telencephalon.
Specimen 1C: embryonic day 10.5; Emx1tm1(cre)Krj/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 1C Loss of expression in the dorsal telencephalon.
Specimen 1E: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 1E Complete loss of expression in the dorsal telencephalon.
Specimen 1F: embryonic day 9.5; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: telencephalon Strong 1F
Specimen 1G: embryonic day 10.0; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: telencephalon Strong 1G Still expressed in the dorsal telencephalon.
Specimen 1H: embryonic day 10.5; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Strong 1H Still expressed in the dorsal telencephalon.
Specimen 1J: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 1J The dorsal telencephalon displayed extensive floxing and loss of expression.
Specimen S1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Strong Widespread S1A Intense expression in the entire cortical neuroepithelium.
Specimen S1B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: telencephalon Strong Widespread S1B Intense expression in the entire cortical neuroepithelium.
Specimen S1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Strong Widespread S1C Intense expression in the entire cortical neuroepithelium.
Specimen S1D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Strong Widespread S1D Intense expression in the entire cortical neuroepithelium.
Specimen S1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pallium Strong Widespread S1E Intense expression in the entire cortical neuroepithelium.
TS20: telencephalon Strong Widespread S1E Intense expression in the entire cortical neuroepithelium.
Specimen S4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present S4A
Specimen S4B: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present S4B Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory