About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:312380 Sun-Wada GH, et al., Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm. Sci Rep. 2021 Sep 29;11(1):19355
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7541115
Gene symbol: Prkcz
Gene name: protein kinase C, zeta
Antibody: anti-PKCzeta
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2a/b/c: embryonic day 5.5 (more )
Note: Triple labeled: green - Prkcz; red - Cdh1 (assay MGI:7541114); blue - Gata6 (assay MGI:7541116).
Structure Level Pattern Image Note
TS7: primitive endoderm Present 2a , 2c , 2b Enriched in the apical region of visceral endoderm cells.
Specimen 2e/f/g: embryonic day 5.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: green - Prkcz; red - Cdh1 (assay MGI:7541114); blue - Gata6 (assay MGI:7541116).
Structure Level Pattern Image Note
TS7: primitive endoderm Present 2f , 2e , 2g More broadly distributed in the cells. The apical surface became rather spherical than flat.
Specimen S3a WT: embryonic day 3.5 (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS4: inner cell mass Present S3a WT right Enriched in the apical region.
TS4: trophectoderm Present S3a WT right Enriched in the apical region.
Specimen S3a -/-: embryonic day 3.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS4: inner cell mass Present S3a -/- right Enriched in the apical region, similar as in the wild-type.
TS4: trophectoderm Present S3a -/- right Enriched in the apical region, similar as in the wild-type.
Specimen S3b WT: embryonic day 4.5 (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS6: primitive endoderm Present S3b WT right Enriched in the apical region of visceral endoderm cells.
Specimen S3b -/-: embryonic day 4.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS6: primitive endoderm Present S3b -/- right Enriched in the apical region, similar as in the wild-type.
Specimen S3c WT: embryonic day 5.0 (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Present S3c WT right Enriched in the apical region of visceral endoderm cells.
Specimen S3c -/-: embryonic day 5.0; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Present S3c -/- right More broadly distributed in the cells.
Specimen S3d WT: embryonic day 5.5 (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Present S3d WT right Enriched in the apical region of visceral endoderm cells.
Specimen S3d -/-: embryonic day 5.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: green - Prkcz; blue - Gata6 (assay MGI:7541116); red - Sox17 (assay MGI:7541133).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Present S3d -/- right More broadly distributed in the cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory