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Gene Expression Data
Assay Details
Assay
Reference: J:321979 Kurz J, et al., Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539749
Gene symbol: Upk1b
Gene name: uroplakin 1B
Antibody: anti-Upk1b (clone 1E1; WH0007348M2)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S6A control: embryonic day 18.5; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS26: urothelium of ureter Present S6A control Upk1b
Specimen S6A Rbpj-cKO: embryonic day 18.5; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: urothelium of ureter Present S6A Rbpj-cKO Upk1b Normal urothelial differentiation was seen in the mutant compared with control.
Specimen S6B control: postnatal day 4; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Cell Type Level Pattern Image Note
TS28: urothelium of ureter basal cell of urothelium Absent S6B control Upk1b
TS28: urothelium of ureter intermediate cell of urothelium Present S6B control Upk1b
TS28: urothelium of ureter umbrella cell of urothelium Present S6B control Upk1b
Specimen S6B Rbpj-cKO: postnatal day 4; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: urothelium of ureter basal cell of urothelium Absent S6B Rbpj-cKO Upk1b Normal urothelial differentiation was seen in the mutant compared with control.
TS28: urothelium of ureter intermediate cell of urothelium Present S6B Rbpj-cKO Upk1b Normal urothelial differentiation was seen in the mutant compared with control.
TS28: urothelium of ureter umbrella cell of urothelium Present S6B Rbpj-cKO Upk1b Normal urothelial differentiation was seen in the mutant compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory