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Gene Expression Data
Assay Details
Assay
Reference: J:206632 Roberts JM, et al., Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol. 2014 Feb 1;522(2):372-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531503
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 8A: embryonic day 10.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Ambiguous 8A

Specimen 8B: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Trace Single cells 8B Rare expressing cells in control brains.

Specimen 8C: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebral cortex Ambiguous 8C

Specimen 8D: embryonic day 15.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex Ambiguous 8D

Specimen 8E: embryonic day 10.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Present Scattered 8E Expression in scattered cells in dorsal regions of cortex.

Specimen 8F: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Strong Widespread 8F Extensive apoptosis throughout cerebral cortex.

Specimen 8G: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebral cortex Present Widespread 8G Widespread expression detected.

Specimen 8H: embryonic day 15.5; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex Ambiguous 8H Authors report ecotopic apoptosis no longer detectable.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory