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Gene Expression Data
Assay Details
Assay
Reference: J:213586 Jackson A, et al., Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis. Dev Dyn. 2014 Sep;243(9):1143-51
Assay type: RNA in situ
MGI Accession ID: MGI:7514575
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 9.5; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS15: branchial pouch Present 2A
Specimen 2A',A'': embryonic day 9.5; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS15: 2nd branchial pouch Present 2A'
TS15: branchial arch ectoderm Present 2A' , 2A'' Expression in pharyngeal ectoderm.
TS15: 3rd branchial pouch Present Regionally restricted 2A' Expression in evaginating pouch 3.
TS15: branchial pouch endoderm Present Regionally restricted 2A' , 2A'' Expression in pouch 4.
Specimen 2B: embryonic day 9.5; Sox17tm2.1(icre)Heli/Sox17+, Tbx1tm2.1Bem/Tbx1tm2.1Bem (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: branchial pouch Present 2B
Specimen 2B',B'': embryonic day 9.5; Sox17tm2.1(icre)Heli/Sox17+, Tbx1tm2.1Bem/Tbx1tm2.1Bem (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 2nd branchial pouch Present 2B'
TS15: branchial arch ectoderm Present 2B' Expression in pharyngeal ectoderm.
TS15: branchial pouch endoderm Weak Regionally restricted 2B' , 2B'' Low expression in a small patch of cells in a presumptive pharyngeal pouch of mutant endoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory