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Gene Expression Data
Assay Details
Assay
Reference: J:308710 Vincentz JW, et al., HAND transcription factors cooperatively specify the aorta and pulmonary trunk. Dev Biol. 2021 Aug;476:1-10
Assay type: RNA in situ
MGI Accession ID: MGI:7513869
Gene symbol: Sema3c
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Probe: Sema3c probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3E: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand1tm2Eno/Hand1+, Hand2tm1Cse/Hand2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: outflow tract migratory cardiac neural crest cell Present 3E
Specimen 3F: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand1tm2Eno/Hand1tm1Eno, Hand2tm1Cse/Hand2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: outflow tract migratory cardiac neural crest cell Present 3F
Specimen 3G: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand1tm1Eno/Hand1+, Hand2tm1Cse/Hand2tm1Dsr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: outflow tract migratory cardiac neural crest cell Present 3G
Specimen 3H: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand1tm1Eno/Hand1tm2Eno, Hand2tm1Cse/Hand2tm1Dsr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: heart migratory cardiac neural crest cell Present 3H This mutant exhibits mis-localized expressing cardiac neural crest cells compared to controls.
TS20: heart septum Present 3H Expression illustrates that this structure is malformed compared to controls.
Specimen S1A: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: outflow tract migratory cardiac neural crest cell Present S1A
Specimen S1B: embryonic day 12.5; Hand1tm1.1(EGFP/cre)Abfi/Hand1+, Hand2tm1Cse/Hand2tm1Cse (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: heart migratory cardiac neural crest cell Present S1B This mutant exhibits mis-localized expressing cells compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/20/2026
MGI 6.24 		The Jackson Laboratory