Gene Expression Data
Assay Details
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Assay
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Reference:
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J:210131
Roy A, et al., Lhx2 regulates the development of the forebrain hem system. Cereb Cortex. 2014 May;24(5):1361-72
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7511692
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Gene symbol:
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Lhx1
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Gene name:
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LIM homeobox protein 1
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Probe:
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Lhx1 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2C:
embryonic day 11.5
(more  )
Specimen
2C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4B Control:
embryonic day 12.5
(more )
Specimen
4B Control:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Cajal-Retzius cell |
Present |
Regionally restricted |
4B Control
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Expressed in the septum.
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Specimen
4B -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lhx2tm1Dra/Lhx2tm1Dra
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Cajal-Retzius cell |
Present |
Regionally restricted |
4B -/-
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A considerable increase in the Cajal-Retzius cells accumulated at the septum.
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Specimen
4I Control:
embryonic day 12.5
(more )
Specimen
4I Control:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4I -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lhx2tm1Dra/Lhx2tm1Dra
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: cortical hem |
Cajal-Retzius cell |
Present |
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4I -/-
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A considerable increase in the Cajal-Retzius cells accumulated in the mantle layer.
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Specimen
S2C Control:
embryonic day 12.5
(more )
Specimen
S2C Control:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
S2C left
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Expressed in the mantle of the thalamic eminence and the thin domain adjacent to the zona limitans intrathalamica.
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Specimen
S2C -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lhx2tm1Dra/Lhx2tm1Dra
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
S2C right
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Expressed in the mantle of the thalamic eminence, which was dramatically expanded in the mutant. Expression in the thin domain adjacent to the zona limitans intrathalamica appeared normal.
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Analysis Tools