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Gene Expression Data
Assay Details
Assay
Reference: J:276652 Fang Q, et al., Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506982
Gene symbol: Ctbp2
Gene name: C-terminal binding protein 2
Antibody: CtBP2 antibody Clone 16 (612044)
Assay notes: Fixation with 4% polyoxymethylene.
Results
Specimen 5a CtBP2 P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P14 WT CtBP2 inset , 5a P14 WT Merged , 5a P14 WT CtBP2 , 5a P14 WT Merged inset Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen 5a CtBP2 P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P14 DKO CtBP2 inset , 5a P14 DKO CtBP2 , 5a P14 DKO Merged inset , 5a P14 DKO Merged No difference in expression compared to wild type from apical to basal turns.
Specimen 5a CtBP2 P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P30 WT CtBP2 inset , 5a P30 WT Merged , 5a P30 WT Merged inset , 5a P30 WT CtBP2 Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen 5a CtBP2 P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P30 DKO Merged , 5a P30 DKO Merged inset , 5a P30 DKO CtBP2 inset , 5a P30 DKO CtBP2 No difference in expression compared to wild type from apical to basal turns.
Specimen S4 CtBP2 APEX P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P14 WT CtBP2 , S4_APEX P14 WT CtBP2 inset , S4_APEX P14 WT Merged , S4_APEX P14 WT Merged Inset
Specimen S4 CtBP2 APEX P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P14 DKO CtBP2 inset , S4_APEX P14 DKO CtBP2 , S4_APEX P14 DKO Merged inset , S4_APEX P14 DKO Merged
Specimen S4 CtBP2 APEX P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P30 WT Merged inset , S4_APEX P30 WT CtBP2 inset , S4_APEX P30 WT CtBP2 , S4_APEX P30 WT Merged
Specimen S4 CtBP2 APEX P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P30 DKO CtBP2 inset , S4_APEX P30 DKO CtBP2 , S4_APEX P30 DKO Merged inset , S4_APEX P30 DKO Merged
Specimen S4 CtBP2 MID P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P14 WT Merged inset , S4_MID P14 WT CtBP2 inset , S4_MID P14 WT CtBP2 , S4_MID P14 WT Merged
Specimen S4 CtBP2 MID P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P14 DKO CtBP2 inset , S4_MID P14 DKO CtBP2 , S4_MID P14 DKO Merged inset , S4_MID P14 DKO Merged
Specimen S4 CtBP2 MID P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P30 WT CtBP2 inset , S4_MID P30 WT Merged , S4_MID P30 WT CtBP2 , S4_MID P30 WT Merged inset
Specimen S4 CtBP2 MID P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P30 DKO Merged inset , S4_MID P30 DKO Merged , S4_MID P30 DKO CtBP2 , S4_MID P30 DKO CtBP2 inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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