About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:209428 Ragancokova D, et al., TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7491893
Gene symbol: Th
Gene name: tyrosine hydroxylase
Results
Specimen S1I Control: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.1Garr (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb glomerular layer Present S1I control
TS26: main olfactory bulb prospective granule cell layer Present S1I control
Specimen S1I Tshz1-/-: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.2Garr (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb prospective granule cell layer Absent S1I Tshz1-/- Loss of expression in granule cell layer.
TS26: main olfactory bulb glomerular layer Present S1I Tshz1-/- Expression in glomerular layer unchanged.
Specimen S1J control: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.1Garr (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb glomerular layer Present S1J control
TS26: main olfactory bulb prospective granule cell layer Present S1J control
Specimen S1J coTshz1: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.1Garr, Tg(Nes-cre)1Kln/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: main olfactory bulb prospective granule cell layer Absent S1J coTshz1 Loss of expression in granule cell layer
TS26: main olfactory bulb glomerular layer Present S1J coTshz1 Expression in glomerular layer unchanged.
Specimen 5B Control: postnatal; Tshz1tm1Garr/Tshz1tm2.1Garr (more )
Note: Double labeled: red - Th; green - Tshz1 reporter (assay MGI:7491839).
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 5B Control
Specimen 5B coTshz1: postnatal; Tshz1tm1Garr/Tshz1tm2.1Garr, Tg(Nes-cre)1Kln/? (more )
Note: Conditional mutant. Double labeled: red - Th; green - Tshz1 reporter (assay MGI:7491839).
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 5B coTshz1 No clear alteration of expresion compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory