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Gene Expression Data
Assay Details
Assay
Reference: J:209428 Ragancokova D, et al., TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7491889
Gene symbol: Tshz1
Gene name: teashirt zinc finger family member 1
Antibody: anti-TSHZ1
Assay notes: Two TSHZ1antibodies were described, but the one used in this assay was not detailed. Anti-TSHZ1 MGI:7491801 may have been used in this assay.
Results
Specimen 1B: postnatal day 0.5 (more )
Note: Double labeled: green - Tshz1; red - Rbfox3 (assay MGI:7491890).
Structure Level Pattern Image Note
TS27: rostral migratory stream Weak 1B , 1B Stream Weak expression in stream of cells migrating from wall of lateral ventricle towards olfactory bulb.
TS27: main olfactory bulb granule cell layer Strong 1B , 1B GCL Strong expression in granule cell layer. Expression co-localized with NeuN (Rbfox3).
Specimen 1C/D: postnatal day 60 (more )
Note: Double labeled: green - Tshz1; red - Rbfox3 (assay MGI:7491890).
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Strong 1C , 1D GCL , 1D Stronger expression in neurons of granule cell layer.
TS28: rostral migratory stream Weak Regionally restricted 1C , 1D RMS , 1D Weak expression within migrating cells of rostral migratory stream that were not NeuN+.
TS28: main olfactory bulb glomerular layer Present Regionally restricted 1D , 1C , 1D GL Expression within subpopulation of neurons in glomerular layer.
Specimen S1H control: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.1Garr (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb Present S1H control
Specimen S1H coTshz1: embryonic day 18.5; Tshz1tm1Garr/Tshz1tm2.1Garr, Tg(Nes-cre)1Kln/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: main olfactory bulb Absent S1H coTshz1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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