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Gene Expression Data
Assay Details
Assay
Reference: J:302538 Ulmke PA, et al., Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling. Development. 2021 Feb 8;148(3):dev188276
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7490333
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Tbr2
Detection system: Secondary antibody
Assay notes: Two Tbr2 antibodies were described, but the one used in this assay was not detailed. Anti-Tbr2 MGI:7490295 may have been used in this assay.
Results
Specimen 3C Rostral Control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present Regionally restricted 3C Rostral Control Expression in basal progenitors.
Specimen 3C Rostral cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present Regionally restricted 3C Rostral cKO Expression in basal progenitors comparable to control.
Specimen 3C Caudal Control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present Regionally restricted 3C Caudal Control Expression in basal progenitors.
Specimen 3C Caudal cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebral cortex subventricular zone Present Regionally restricted 3C Caudal cKO Expression in basal progenitors comparable to control.
Specimen 4B Control: embryonic day 13.5 (more )
Note: Double labeled: green - Eomes; red - Casp3 (assay MGI:7490334).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4B Control inset , 4B Control Expression in basal progenitors.
Specimen 4B cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: green - Eomes; red - Casp3 (assay MGI:7490334).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4B cKO inset , 4B cKO Co-expression with Casp3 in basal progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory