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Gene Expression Data
Assay Details
Assay
Reference: J:302538 Ulmke PA, et al., Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling. Development. 2021 Feb 8;148(3):dev188276
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7490334
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-Casp3
Detection system: Secondary antibody
Results
Specimen E11.5 Control not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Absent
Specimen E11.5 cKO not shown: embryonic day 11.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Present
Specimen E12.5 Control not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Absent
Specimen E12.5 cKO not shown: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebral cortex Present
Specimen 4A Control: embryonic day 13.5 (more )
Note: Double labeled: red - Casp3; green - Sox2 (assay MGI:7490321).
Structure Level Pattern Image Note
TS21: cerebral cortex Absent 4A Control inset , 4A Control
Specimen 4A cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Sox2 (assay MGI:7490321).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4A cKO inset , 4A cKO Expression especially in rostromedial area. Expression in entire cortex, more dominant on basal side of cortical wall.
Specimen 4B Control: embryonic day 13.5 (more )
Note: Double labeled: red - Casp3; green - Eomes (assay MGI:7490333).
Structure Level Pattern Image Note
TS21: cerebral cortex Absent 4B Control inset , 4B Control
Specimen 4B cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Eomes (assay MGI:7490333).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4B cKO inset , 4B cKO Expression especially in rostromedial area. Expression in entire cortex, more dominant on basal side of cortical wall.
Specimen 4C Control: embryonic day 13.5 (more )
Note: Double labeled: red - Casp3; green - Rbfox3 (assay MGI:7490323).
Structure Level Pattern Image Note
TS21: cerebral cortex Absent 4C Control , 4C Control inset
Specimen 4C cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Rbfox3 (assay MGI:7490323).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 4C cKO inset , 4C cKO Expression especially in rostromedial area. Expression in entire cortex, more dominant on basal side of cortical wall.
Specimen S3 Control: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S3_Control (lower) , S3_Control (upper)
Specimen S3 Mut 1: postnatal day 6; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S3_Mut 1 (lower) , S3_Mut 1 (upper)
Specimen S3 Mut 2: postnatal day 6; Emx1tm1(cre)Krj/Emx1+, Exosc10tm1.1Vlcg/Exosc10tm1.1Vlcg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S3_Mut 2 (lower) , S3_Mut 2 (upper)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory