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Gene Expression Data
Assay Details
Assay
Reference: J:336140 Yokomizo T, et al., Independent origins of fetal liver haematopoietic stem and progenitor cells. Nature. 2022 Sep;609(7928):779-784
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7489674
Gene symbol: Mecom
Gene name: MDS1 and EVI1 complex locus
Reporter: GFP
Antibody: anti-GFP
Results
Specimen 2c AGM: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Triple labeled: green - Mecom reporter; red - Kit (assay MGI:7489679); white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: dorsal aorta endothelium Strong 2c AGM (merge) , 2c AGM GFP
Specimen 2c Yolk sac: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Triple labeled: green - Mecom reporter; red - Kit (assay MGI:7489679); white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Weak Regionally restricted 2c Yolk sac GFP , 2c Yolk sac (merge) Low expression in yolk sac arteries.
Specimen ED5a Embryo: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: dorsal aorta endothelium Strong ED5a Embryo (merge) , ED5a Embryo GFP
Specimen ED5a Yolk sac: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Weak Regionally restricted ED5a Yolk sac GFP , ED5a Yolk sac (merge) Low expression in yolk sac arteries. Expression restricted to artery around entrance of yolk sac.
Specimen ED5b Umbilical artery: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: umbilical artery Strong ED5b Umbilical artery merge , ED5b Umbilical artery GFP
Specimen ED5b Vitelline artery: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: vitelline artery Strong ED5b Vitelline artery GFP , ED5b Vitelline artery merge
Specimen ED5b Umbilical vein: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; white - Pecam1 (assay MGI:7489680).
Structure Level Pattern Image Note
TS17: umbilical vein Absent ED5b Umbilical vein merge , ED5b Umbilical vein GFP
Specimen ED7g AGM: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; red - Hlf reporter (assay MGI:7489681).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted ED7g AGM Merge , ED7g AGM GFP Expression in hematopoietic clusters.
Specimen ED7g Yolk sac: embryonic day 10.5; Mecomtm2Miku/Mecom+ (more )
Note: Double labeled: green - Mecom reporter; red - Hlf reporter (assay MGI:7489681).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Weak ED7g Yolk sac GFP , ED7g Yolk sac Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory