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Gene Expression Data
Assay Details
Assay
Reference: J:192269 Mukhopadhyay A, et al., Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15;373(2):373-82
Assay type: RNA in situ
MGI Accession ID: MGI:7484200
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 9B Control: postnatal day 7 (more )
Note: Skin from littermate wild-type control (genotype was not specified).
Structure Level Pattern Image Note
TS28: hair bulb Present 9B control
TS28: hair follicle Present 9B control
Specimen 9B Fgfr2cKO: postnatal day 7; Fgfr2tm1Dor/Fgfr2tm1.1Dor, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hair follicle Present 9B cKO Overall expression pattern was unchanged.
TS28: hair bulb Present 9B cKO Similar number of positive cells in hair bulb region as in the control (summarized in Fig 9C).
Specimen not shown: postnatal day 7 (more )
Note: Skin from littermate wild-type control (genotype was not specified).
Structure Level Pattern Image Note
TS28: hair bulb Present
Specimen not shown: postnatal day 7; Krastm4Tyj/Kras+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hair bulb Present Similar number of positive cells in hair bulb region as in the control (summarized in Fig 9C).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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