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Gene Expression Data
Assay Details
Assay
Reference: J:126484 Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7481308
Gene symbol: Mrgprd
Gene name: MAS-related GPR, member D
Reporter: GFP
Direct Detection
Results
Specimen 4A: postnatal day 14; Mrgprdtm1Mjz/Mrgprd+, Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 4A Expression in abundant nonpeptidergic fibers.
Specimen 4B: postnatal day 14; Mrgprdtm1Mjz/?, Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 4B Expression in nonpeptidergic fibers.
Specimen 4E/G: postnatal day 14; Mrgprdtm1Mjz/Mrgprd+, Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: epidermis Strong Regionally restricted 4E , 4G Strong expression in abundant fibers, with free nerve endings terminating in stratum granulosum.
Specimen 4F/H: postnatal day 14; Mrgprdtm1Mjz/?, Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: epidermis Weak Punctate 4F , 4H Weak expression in punctate manner. Substantial reduction in number of fibers innervating epidermis.
Specimen 4I: postnatal day 14; Mrgprdtm1Mjz/Mrgprd+, Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: spinal cord thoracic region Present Regionally restricted 4I Expression in nonpeptidergic fibers.
Specimen 4I inset: postnatal day 14; Mrgprdtm1Mjz/Mrgprd+, Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: spinal cord thoracic region Present Regionally restricted 4I inset Central projections formed distinct layers
Specimen 4J: postnatal day 14; Mrgprdtm1Mjz/?, Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: spinal cord thoracic region Present Regionally restricted 4J Expression in nonpeptidergic fibers.
Specimen 4J inset: postnatal day 14; Mrgprdtm1Mjz/?, Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - MrgD (Mrgprd) reporter; red - CGRP (Calca assay MGI:7481301).
Structure Level Pattern Image Note
TS28: spinal cord thoracic region Present Regionally restricted 4J inset No difference in lamina specific innervation on nonpeptidergic fibers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory