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Gene Expression Data
Assay Details
Assay
Reference: J:249358 Shpargel KB, et al., UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9046-E9055
Assay type: RNA in situ
MGI Accession ID: MGI:7471468
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch cDNA
Probe preparation: Antisense RNA
Results
Specimen 5F WT left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 5F WT left
TS17: face Present 5F WT left
Specimen 5F WT right: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 5F WT right
TS17: face Present 5F WT right
Specimen 5F FKO left: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Kdm6atm1c(EUCOMM)Wtsi/Kdm6atm1c(EUCOMM)Wtsi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: embryo Present 5F FKO left Reduced expression compared with the wild-type, particularly in cranial regions.
TS17: face Present 5F FKO left Reduced expression compared with the wild-type.
Specimen 5F FKO right: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Kdm6atm1c(EUCOMM)Wtsi/Kdm6atm1c(EUCOMM)Wtsi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: embryo Present 5F FKO right Reduced expression compared with the wild-type, particularly in cranial regions.
TS17: face Present 5F FKO right Reduced expression compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory