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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449015
Gene symbol: Bmp10
Gene name: bone morphogenetic protein 10
Antibody: anti-BMP10 (AP1710a)
Detection system: Secondary antibody
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen S7A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present S7A E10.5 (lower) , S7A E10.5 (upper)
Specimen S7A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S7A E11.5 (upper) , S7A E11.5 (lower)
Specimen S7A E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trabecular myocardium Present Regionally restricted S7A E12.5 (upper) , S7A E12.5 (lower) Expression becomes restricted to trabecular component after E12.5.
Specimen S7A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trabecular myocardium Present S7A E13.5 (upper) , S7A E13.5 (lower) Expression becomes restricted to trabecular component after E12.5.
Specimen S7A E15..5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: trabecular myocardium Present S7A E15.5 (lower) , S7A E15.5 (upper) Expression becomes restricted to trabecular component after E12.5.
Specimen S7C E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S7C E11.5 Control
Specimen S7C E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S7C E11.5 Cre/+ Expression similar to that of control.
TS19: myocardium layer Present Regionally restricted S7C E11.5 Cre/+ Ectopic expression in left ventricular compact zone.
Specimen S7C E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS20: trabecular myocardium Present S7C E12.5 Control
Specimen S7C E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: trabecular myocardium Present S7C E12.5 Cre/+ Expression similar to that of control.
TS20: compact myocardium Present Regionally restricted S7C E12.5 Cre/+ Ectopic expression in left ventricular compact zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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