About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449014
Gene symbol: Nppa
Gene name: natriuretic peptide type A
Antibody: anti-NPPA (27426-1-AP)
Detection system: Secondary antibody
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen 3A E10.5 Control: embryonic day 10.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 3A E10.5 Control
Specimen 3A E10.5 Cre/+: embryonic day 10.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 3A E10.5 Cre/+
Specimen 3A E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS19: trabecular myocardium Present 3A E11.5 Control Expression becomes restricted to trabecular component after E10.5
Specimen 3A E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present Regionally restricted 3A E11.5 Cre/+ Authors report ectopic expression in left ventricular compact zone at E11.5
Specimen 3A E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS20: trabecular myocardium Present 3A E12.5 Control
Specimen 3A E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: compact myocardium Present Regionally restricted 3A E12.5 Cre/+ Authors report ectopic expression in left ventricular compact zone at E12.5
Specimen 4E E13.5 Control: embryonic day 13.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS21: trabecular myocardium Present 4E E13.5 Control
Specimen 4E E13.5 Cre/+: embryonic day 13.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: trabecular myocardium Present 4E E13.5 Cre/+ Trabecula develop normally compared to control.
Specimen 4E E15.5 Control: embryonic day 15.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS23: trabecular myocardium Present 4E E15.5 Control
Specimen 4E E15.5 Cre/+: embryonic day 15.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: trabecular myocardium Present 4E E15.5 Cre/+ Trabecula develop normally compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory