Nefh Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:333563 Schneider F, et al., Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function. Prog Neurobiol. 2021 Jul;202:102050
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7444042
Gene symbol:	Nefh
Gene name:	neurofilament, heavy polypeptide

Antibody:	anti-NF200
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1F CTR ©

1F CTR inset ©

Specimen 1F CTR: embryonic day 18.5; Cap1^tm1.1Mbrst/Cap1^tm1.1Mbrst (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex intermediate zone	Present		1F CTR inset , 1F CTR
TS26: corpus striatum	Present		1F CTR inset , 1F CTR

1F CAP1-KO ©

Specimen 1F CAP-KO: embryonic day 18.5; Cap1^tm1.1Mbrst/Cap1^tm1.1Mbrst, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex intermediate zone	Present	Regionally restricted	1F CAP1-KO , 1F CAP1-KO inset	Less fiber tracts in cortical intermediate zone and striatum.
TS26: corpus striatum	Present	Regionally restricted	1F CAP1-KO , 1F CAP1-KO inset	Less fiber tracts in cortical intermediate zone and striatum.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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