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Gene Expression Data
Assay Details
Assay
Reference: J:283394 Hughes LJ, et al., Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7434578
Gene symbol: Myh10
Gene name: myosin, heavy polypeptide 10, non-muscle
Antibody: Anti-Myosin IIB (PRB-445P)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 8C/C': embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted 8C' , 8C Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.
Specimen 8D/D': embryonic day 13.5; Tg(Nes-cre)1Atp/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: cerebellum ventricular layer neuroepithelial stem cell Absent 8D' , 8D
Specimen 8I/I': embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted 8I , 8I' Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.
Specimen 8J/J': embryonic day 16.5; Tg(Nes-cre)1Atp/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Absent 8J' , 8J
Specimen 8O: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted 8O Expressed at the ventricular surface continuously.
Specimen 8P: embryonic day 16.5; Tg(GFAP-cre)25Mes/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted 8P Loss of apical localization of Myh10 correlated with the Yap1-reduced area.
Specimen S8C: postnatal day 7 (more )
Note: Double labeled: red - Myh10; green - Ctnnb1 (assay MGI:7434581).
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S8C middle , S8C merge , S8C right Localized in the cell junction.
Specimen S8D: postnatal day 7; Tg(Nes-cre)1Atp/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: red - Myh10; green - Ctnnb1 (assay MGI:7434581).
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S8D middle , S8D merge , S8D right Localized in the cell junction, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory