Ctnnb1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:283394 Hughes LJ, et al., Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7434581
Gene symbol:	Ctnnb1
Gene name:	catenin beta 1

Antibody:	anti-beta-catenin (#610153), clone 14
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

8G ©

Specimen 8G: embryonic day 16.5 (more

)
Note: Double labeled: green - Ctnnb1; red - Crb1 (assay MGI:7434580), Crb2 (assay MGI:7435350) and Crb3 (assay MGI:7435351).

Structure	Cell Type	Level	Pattern	Image	Note
TS24: cerebellum ventricular layer	neuroepithelial stem cell	Present	Regionally restricted	8G	Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.

8H ©

Specimen 8H: embryonic day 16.5; Tg(Nes-cre)1Atp/0, Wwtr1^tm1.1Eno/Wwtr1^tm1.1Eno, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant. Double labeled: green - Ctnnb1; red - Crb1 (assay MGI:7434580), Crb2 (assay MGI:7435350) and Crb3 (assay MGI:7435351).

Structure	Cell Type	Level	Pattern	Image	Note
TS24: cerebellum ventricular layer	neuroepithelial stem cell	Absent		8H

S8C left ©

S8C merge ©

S8C right ©

Specimen S8C: postnatal day 7 (more

)
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7434578).

Structure	Level	Pattern	Image	Note
TS28: cerebellum external granule cell layer	Present		S8C right , S8C merge , S8C left	Localized in the cell junction.

S8D left ©

S8D merge ©

S8D right ©

Specimen S8D: postnatal day 7; Tg(Nes-cre)1Atp/0, Wwtr1^tm1.1Eno/Wwtr1^tm1.1Eno, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant. Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7434578).

Structure	Level	Pattern	Image	Note
TS28: cerebellum external granule cell layer	Present		S8D merge , S8D right , S8D left	Localized in the cell junction, similar as in the wild-type.

Specimen not shown: embryonic day 13.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS21: cerebellum ventricular layer	neuroepithelial stem cell	Present	Regionally restricted		Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.

Specimen not shown: embryonic day 13.5; Tg(Nes-cre)1Atp/0, Wwtr1^tm1.1Eno/Wwtr1^tm1.1Eno, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS21: cerebellum ventricular layer	neuroepithelial stem cell	Present	Regionally restricted		Partially lost expression at the ventricular surface.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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