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Gene Expression Data
Assay Details
Assay
Reference: J:331875 Wischhof L, et al., BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation. EMBO J. 2022 Dec 1;41(23):e110595
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7410995
Gene symbol: Bcl7a
Gene name: B cell CLL/lymphoma 7A
Results
Specimen 1I E17.5: embryonic day 17.5 (more )
Note: Triple labeled: magenta - Bcl7a; green - Edu; white - NeuN (Rbfox3 assay MGI:7410996).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus hippocampal neuron Present 1I E17.5 , 1I E17.5 (merge) , 1I E17.5 BCL7A Expression in nuclei of NeuN-expressing neurons and also in non-NeuN-expressing cells.
Specimen 1I PD120: postnatal day 120 (more )
Note: Triple labeled: magenta - Bcl7a; green - Edu; white - NeuN (Rbfox3 assay MGI:7410996).
Structure Cell Type Level Pattern Image Note
TS28: hippocampus hippocampal neuron Present 1I PD120 , 1I PD120 BCL7A , 1I PD120 (merge) Expression in nuclei of NeuN-expressing neurons and also in non-NeuN-expressing cells.
Specimen 3D Nestin-Cre: postnatal adult; Tg(Nes-cre)1Kln/0 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 3D Nestin-Cre
Specimen 3D fl/fl;Nestin-Cre: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Absent 3D fl/fl/Nestin-Cre
Specimen EV3A Nestin-Cre: postnatal day 3; Tg(Nes-cre)1Kln/0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present EV3A wt/wt;Nestin-Cre
TS27: hippocampus Present EV3A wt/wt;Nestin-Cre
Specimen EV3A fl/fl;Nestin-Cre: postnatal day 3; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cerebral cortex Trace Single cells EV3A fl/fl;Nestin-Cre Several expressing cells within cortex and hippocampus.
TS27: hippocampus Trace Single cells EV3A fl/fl;Nestin-Cre Several expressing cells within cortex and hippocampus.
Specimen 3H fl/fl: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 3H fl/fl
Specimen 3H fl/fl;Baf53b-Cre: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Actl6b-cre)4092Jiwu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 3H Baf53b-Cre Expression still detectable in proliferating neuroblasts.
Specimen 3I fl/fl: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban (more )
Note: Double labeled: red - Bcl7a; green - Dcx (assay MGI:7410997).
Structure Level Pattern Image Note
TS28: hippocampus Present 3I fl/fl (merge) , 3I fl/fl BCL7A
Specimen 3I fl/fl;Baf53b-Cre: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Actl6b-cre)4092Jiwu/0 (more )
Note: Conditional mutant. Double labeled: red - Bcl7a; green - Dcx (assay MGI:7410997).
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 3I Baf53b-Cre (merge) , 3I Baf53b-Cre BCL7A Expression still detectable in Dcx-expressing lacking neurite outgrowth.
Specimen EV4C control: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban (more )
Note: Triple labeled: green - Bcl7a; red - NeuN (Rbfox3 assay MGI:7410996); white - Gfap (assay MGI:7410999).
Structure Level Pattern Image Note
TS28: hippocampus Present EV4C control inset BCL7a (lower) , EV4C control inset (merge upper) , EV4C control inset (merge lower) , EV4C control , EV4C control inset BCL7a (upper)
Specimen EV4C fl/fl:BAF3b-Cre: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Actl6b-cre)4092Jiwu/0 (more )
Note: Conditional mutant. Triple labeled: green - Bcl7a; red - NeuN (Rbfox3 assay MGI:7410996); white - Gfap (assay MGI:7410999).
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted EV4C BAF53-Cre inset (merge) , EV4C BAF53-Cre inset BCL7a , EV4C BAF53-Cre No expression in postmitotic neurons.
Specimen EV4C fl/fl:Nestin-Cre: postnatal adult; Bcl7atm1Ban/Bcl7atm1Ban, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: green - Bcl7a; red - NeuN (Rbfox3 assay MGI:7410996); white - Gfap (assay MGI:7410999).
Structure Level Pattern Image Note
TS28: hippocampus Absent EV4C Nestin-Cre inset (merge) , EV4C Nestin-Cre inset BCL7a , EV4C Nestin-Cre
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory