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Gene Expression Data
Assay Details
Assay
Reference: J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378741
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase 3
Detection system: Secondary antibody coupled to DyLight 549
Results
Specimen 4A: embryonic day 15.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Trace Single cells 4A Expression in few cells.
TS23: cerebral cortex subventricular zone Trace Single cells 4A Expression in few cells.
TS23: cerebral cortex intermediate zone Trace Single cells 4A Expression in few cells.
TS23: cortical plate Absent 4A

Specimen 4B: embryonic day 15.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Trace Single cells 4B Density of expressing cells similar to that of ontrols.
TS23: cerebral cortex subventricular zone Trace Single cells 4B Density of expressing cells similar to that of ontrols.
TS23: cerebral cortex intermediate zone Trace Single cells 4B Density of expressing cells similar to that of ontrols.
TS23: cortical plate Present Single cells 4B Density of expressing cells in cortical plate increased compared to controls.

Specimen 4G: embryonic day 18.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Trace Single cells 4G Expression in few cells.
TS26: cerebral cortex subventricular zone Trace Single cells 4G Expression in few cells.
TS26: cerebral cortex intermediate zone Trace Single cells 4G Expression in few cells.

Specimen 4H: embryonic day 18.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Trace Single cells 4H Density of expressing cells similar to that of controls.
TS26: cerebral cortex subventricular zone Trace Single cells 4H Density of expressing cells similar to that of controls.
TS26: cerebral cortex intermediate zone Trace Single cells 4H Density of expressing cells similar to that of controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory