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Gene Expression Data
Assay Details
Assay
Reference: J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378736
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-SOX2
Detection system: Secondary antibody coupled to DyLight 549
Results
Specimen 1A: embryonic day 12.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Double labeled: red - Sox2; green - Yap1 (assay MGI:7378735).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 1A (upper)
Specimen 1B: embryonic day 12.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant. Double labeled: red - Sox2; green - Yap1 (assay MGI:7378735).
Structure Level Pattern Image Note
TS20: cerebral cortex Present 1B (upper)
Specimen 6A: embryonic day 15.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 6A Most expressing cells located in subventricular zone and ventricular zone.
TS23: cerebral cortex subventricular zone Present 6A Most expressing cells located in subventricular zone and ventricular zone.
TS23: cerebral cortex intermediate zone Weak 6A
Specimen 6B: embryonic day 15.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 6B Expression similar to that of controls.
TS23: cerebral cortex subventricular zone Present 6B Expression similar to that of controls.
TS23: cerebral cortex intermediate zone Weak 6B Expression similar to that of controls.
Specimen 6G: embryonic day 18.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Present 6G Most expressing cells located in subventricular zone and ventricular zone.
TS26: cerebral cortex subventricular zone Present 6G Most expressing cells located in subventricular zone and ventricular zone.
TS26: cerebral cortex intermediate zone Present 6G Some expressing cells located in intermediate zone.
Specimen 6H: embryonic day 18.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Present 6H Expression similar to that of controls.
TS26: cerebral cortex subventricular zone Present 6H Expression similar to that of controls.
TS26: cerebral cortex intermediate zone Present 6H Expression similar to that of controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory