Yap1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7378735
Gene symbol:	Yap1
Gene name:	yes-associated protein 1

Antibody:	anti-YAP
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1A (lower) ©

1A (upper) ©

Specimen 1A: embryonic day 12.5; Yap1^tm1.1Dupa/Yap1^tm1.1Dupa (more

)
Note: Double labeled: green - Yap1; red - Sox2 (assay MGI:7378736).

Structure	Level	Pattern	Image	Note
TS20: cerebral cortex ventricular layer	Strong	Regionally restricted	1A (lower) , 1A (upper)	High level of expression in ventricular zone. Most expression distributed in cytoplasm.

1B (lower) ©

1B (upper) ©

Specimen 1B: embryonic day 12.5; Tg(Nes-cre)1Kln/0, Yap1^tm1.1Dupa/Yap1^tm1.1Dupa (more

)
Note: Conditional mutant. Double labeled: green - Yap1; red - Sox2 (assay MGI:7378736).

Structure	Level	Pattern	Image	Note
TS20: cerebral cortex	Trace		1B (upper) , 1B (lower)	Level of expression reduced compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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