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Gene Expression Data
Assay Details
Assay
Reference: J:284490 Varum S, et al., Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7332923
Gene symbol: Pou4f1
Gene name: POU domain, class 4, transcription factor 1
Antibody: anti-Brn3a
Detection system: Secondary antibody coupled to Cy3
Results
Specimen S1E Control: embryonic day 11.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: red - Brn3a (Pou4f1); green - Nefm (assay MGI:7332915).
Structure Cell Type Level Pattern Image Note
TS19: dorsal root ganglion sensory neuron Present S1E Control
Specimen S1E Yy1 cko: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: red - Brn3a (Pou4f1); green - Nefm (assay MGI:7332915).
Structure Cell Type Level Pattern Image Note
TS19: dorsal root ganglion sensory neuron Present S1E Yy1 cko Reduced size of dorsal root ganglia, but normal differentiation of DRG cells.
Specimen 1N Control: embryonic day 13.5; Yy1tm2Yshi/Yy1+ (more )
Note: Control could be Yy1fl/+; Yy1fl/fl or Yy1fl/+;Wnt1-Cre. Double labeled: red - Brn3a (Pou4f1); green - Nefm (assay MGI:7332915).
Structure Cell Type Level Pattern Image Note
TS21: dorsal root ganglion sensory neuron Present 1N Control
Specimen 1N Yy1 cko: embryonic day 13.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Yy1tm2Yshi/Yy1tm2Yshi (more )
Note: Conditional mutant. Double labeled: red - Brn3a (Pou4f1); green - Nefm (assay MGI:7332915).
Structure Cell Type Level Pattern Image Note
TS21: dorsal root ganglion sensory neuron Present 1N Yy1 cko Reduced size of dorsal root ganglia, but normal differentiation of DRG cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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