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Gene Expression Data
Assay Details
Assay
Reference: J:271028 Albers E, et al., Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality. Cell Rep. 2018 Sep 18;24(12):3274-3284
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7311705
Gene symbol: H2ax
Gene name: H2A.X variant histone
Antibody: anti-phosphoH2AX (#05-636; JBW301)
Detection system: horseradish peroxidase
Results
Specimen 2A Pich WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Trace 2A Pich WT
Specimen 2A Pich Het: embryonic day 10.5; Ercc6ltm1.1Ajlc/Ercc6l+ (more )
Structure Level Pattern Image Note
TS17: embryo Trace 2A Pich Het
Specimen 2A Pich KO: embryonic day 10.5; Ercc6ltm1.1Ajlc/Ercc6ltm1.1Ajlc (more )
Structure Level Pattern Image Note
TS17: embryo Present 2A Pich KO Increase in proportion of expressing cells.
Specimen S1E Pich Het: embryonic day 10.5; Ercc6ltm1.1Ajlc/Ercc6l+ (more )
Structure Level Pattern Image Note
TS17: embryo Ambiguous S1E Pich Het Expression in specimen not described.
Specimen S1E Pich KO: embryonic day 10.5; Ercc6ltm1.1Ajlc/Ercc6ltm1.1Ajlc (more )
Structure Level Pattern Image Note
TS17: embryo Present S1E Pich KO Increase in proportion of expressing cells.
Specimen S2B Pich WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Ambiguous S2B Pich WT Expression in specimen not described.
Specimen S2B Pich KO: embryonic day 11.5; Ercc6ltm1.1Ajlc/Ercc6ltm1.1Ajlc (more )
Structure Level Pattern Image Note
TS19: embryo Present S2B Pich KO
Specimen S3B Pich WT: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Trace S3B Pich WT
Specimen S3B Pich KO: embryonic day 12.5; Ercc6ltm1.1Ajlc/Ercc6ltm1.1Ajlc (more )
Structure Level Pattern Image Note
TS20: embryo Trace S3B Pich KO
Specimen S5B H2ax WT (left): embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Ambiguous S5B WT yH2AX (left) Expression in specimen not described.
Specimen S5B H2ax WT (right): embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Ambiguous S5B WT yH2AX (right) Expression in specimen not described.
Specimen S5B H2ax Ptch KO: embryonic day 10.5; Ercc6ltm1.1Ajlc/Ercc6ltm1.1Ajlc (more )
Structure Level Pattern Image Note
TS17: embryo Present S5B Pich KO yH2AX
Specimen S5B H2ax Trp53 Het (left): embryonic day 10.5; Ercc6ltm1.2Ajlc/Ercc6ltm1.2Ajlc, Trp53tm1Tyj/Trp53+ (more )
Structure Level Pattern Image Note
TS17: embryo Present S5B Trp53 Het yH2AX (left)
Specimen S5B H2ax Trp53 Het (right): embryonic day 10.5; Ercc6ltm1.2Ajlc/Ercc6ltm1.2Ajlc, Trp53tm1Tyj/Trp53+ (more )
Structure Level Pattern Image Note
TS17: embryo Present S5B Trp53 Het yH2AX (right)
Specimen S5B H2ax Trp53 KO (left): embryonic day 10.5; Ercc6ltm1.2Ajlc/Ercc6ltm1.2Ajlc, Trp53tm1Tyj/Trp53tm1Tyj (more )
Structure Level Pattern Image Note
TS17: embryo Present S5B Trp53 KO yH2AX (left)
Specimen S5B H2ax Trp53 KO (right): embryonic day 10.5; Ercc6ltm1.2Ajlc/Ercc6ltm1.2Ajlc, Trp53tm1Tyj/Trp53tm1Tyj (more )
Structure Level Pattern Image Note
TS17: embryo Present S5B Trp53 KO yH2AX (right)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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