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Antibody
Detail
Antibody
Name: anti-phosphoH2AX (#05-636; JBW301)
Host: mouse
Type: Monoclonal
Class: IgG1
Note: This antibody was obtained from Millipore/Upstate (#05-636). Recognizes Histone H2A.X when phosphorylated at serine 139, indicative of DNA damage.
MGI Accession ID: MGI:5305847
Antigen
Name: gammaH2A.X
Species: human
Region covered: amino acids 134-142 - CKATQA[pS]QEY
Note: The immunogen was a synthetic peptide conjugated to keyhole limpet hemocyanin. The sequence has 8 identical amino acids in yeast and mouse.
Gene H2ax  H2A.X variant histone
Expression Gene Expression Data (147 results)
References J:175085 Le Masson F, et al., Mol Cell Biol. 2011 Aug;31(16):3410-23
J:138760 Reynard LN, et al., Biol Reprod. 2007 Aug;77(2):329-35
J:164280 Bowles J, et al., Dev Cell. 2010 Sep 14;19(3):440-9
J:180706 Gruber R, et al., Nat Cell Biol. 2011 Nov;13(11):1325-34
J:229524 Robert T, et al., Science. 2016 Feb 26;351(6276):943-9
J:231231 Abby E, et al., Nat Commun. 2016;7:10324
J:236351 Ahuja AK, et al., Nat Commun. 2016 Feb 15;7:10660
J:236776 Balmus G, et al., Genes Dev. 2016 Oct 1;30(19):2152-2157
J:240025 Zhou L, et al., Dev Cell. 2017 Mar 13;40(5):453-466.e5
J:256987 Shi B, et al., PLoS Genet. 2018 Jan;14(1):e1007175
J:264258 Miyamoto Y, et al., Biol Open. 2018 Aug 6;7(8):bio032631
J:266583 Baumgartner M, et al., Development. 2018 Aug 28;145(17):dev166322
J:271028 Albers E, et al., Cell Rep. 2018 Sep 18;24(12):3274-3284
J:278517 Li M, et al., Sci Adv. 2019;5(8):eaax1101
J:285969 Liu H, et al., Nucleic Acids Res. 2019 Jun 20;47(11):5670-5683
J:309183 Gomes AL, et al., Front Cell Dev Biol. 2020;8:711
J:303646 Li M, et al., Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2025421118
J:311932 White AK, et al., Development. 2021 Oct 15;148(20):dev199591
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory