Smn1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:159448 Mende Y, et al., Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing. Hum Mol Genet. 2010 Jun 1;19(11):2154-67
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7285995
Gene symbol:	Smn1
Gene name:	survival motor neuron 1

Antibody:	anti-SMN
Detection system:	Biotinylated secondary antibody/[Strept]avidin

Results

Specimen 6A Smn: postnatal adult; Tra2b^tm1.1Bwir/Tra2b^tm1.1Bwir (more

)
Note: Double labeled: blue - Smn1; brown - Sfrs10 (Tra2b assay MGI:7285994).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: spinal cord	motor neuron	Present		6A

Specimen 6B Smn: postnatal adult; Mnx1^tm4(cre)Tmj/Mnx1⁺, Tra2b^tm1.1Bwir/Tra2b^tm1.1Bwir (more

)
Note: Conditional mutant. Double labeled: blue - Smn1; brown - Sfrs10 (Tra2b assay MGI:7285994).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: spinal cord	motor neuron	Present		6B	Expression unchanged compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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