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Gene Expression Data
Assay Details
Assay
Reference: J:308695 Talley MJ, et al., Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon. Front Cell Dev Biol. 2021;9:673995
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281561
Gene symbol: Tcf7l2
Gene name: transcription factor 7 like 2, T cell specific, HMG box
Results
Specimen 3E: postnatal month 1; Lztr1tm1c(EUCOMM)Wtsi/Lztr1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present Regionally restricted 3E Expression was detected in differentiating oligodendrocytes.
Specimen 3F: postnatal month 1; Lztr1tm1b(EUCOMM)Wtsi/Lztr1tm1c(EUCOMM)Wtsi, Foxg1tm1.1(cre)Ddmo/Foxg1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present Regionally restricted 3F Expression was decreased 26% in differentiating oligodendrocytes in the conditional mutant compared with control corpus callosum.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory