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Gene Expression Data
Assay Details
Assay
Reference: J:308695 Talley MJ, et al., Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon. Front Cell Dev Biol. 2021;9:673995
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281526
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Results
Specimen 2K: postnatal day 21; Lztr1tm1b(EUCOMM)Wtsi/Lztr1+ (more )
Note: Double labeled: red - Olig2; green - Lztr1 reporter (assay MGI:7281496).
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present 2K Olig2 is a marker of the entire oligodendrocyte lineage. Expression of Olig2 overlapped with beta-gal staining for Lztr1. However, there were many cells stained only with Olig2.
Specimen 3A: postnatal month 1; Lztr1tm1c(EUCOMM)Wtsi/Lztr1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present 3A Expression was detected in the entire oligodendrocyte lineage.
Specimen 3B: postnatal month 1; Lztr1tm1b(EUCOMM)Wtsi/Lztr1tm1c(EUCOMM)Wtsi, Foxg1tm1.1(cre)Ddmo/Foxg1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present 3B No difference was noted in the number of Olig2-positive cells between control and conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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