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Gene Expression Data
Assay Details
Assay
Reference: J:308695 Talley MJ, et al., Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon. Front Cell Dev Biol. 2021;9:673995
Assay type: RNA in situ
MGI Accession ID: MGI:7281487
Gene symbol: Lztr1
Gene name: leucine-zipper-like transcriptional regulator, 1
Probe: Lztr1 probe1
Probe preparation: Antisense
Results
Specimen 1A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 1A Expression was enriched in the mantle zone of the developing cortex.
TS26: telencephalon Weak Regionally restricted 1A Weak expression was detected around the telencephalic ventricles. Staining was more apparent at the rostral levels.
Specimen 1B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 1B Expression was enriched in the mantle zone of the developing cortex.
TS26: dorsal thalamus Present 1B
TS26: trigeminal nerve Present 1B
Specimen 1C: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Widespread 1C
Specimen 1D: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Widespread 1D
TS28: basolateral amygdaloid nucleus Present 1D
TS28: hippocampus Present 1D
TS28: thalamus Present 1D
Specimen 1K: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 1K
Specimen 2A: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2A
TS28: hippocampus Present 2A
Specimen 2B: postnatal day 21; Lztr1tm1b(EUCOMM)Wtsi/Lztr1tm1c(EUCOMM)Wtsi, Foxg1tm1.1(cre)Ddmo/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Weak 2B
TS28: hippocampus Weak 2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory