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Gene Expression Data
Assay Details
Assay
Reference: J:132315 Lynn FC, et al., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007 Dec;56(12):2938-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266738
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated caspase3
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6G: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pdx1 (assay MGI:7266723).
Structure Level Pattern Image Note
TS23: pancreatic duct Present 6G
TS23: pancreas mesenchyme Present 6G
Specimen 6H: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pdx1 (assay MGI:7266723).
Structure Level Pattern Image Note
TS23: pancreatic duct Strong 6H Significantly increased expression in ductal cords compared with control limited to eithelial cells.
TS23: pancreas mesenchyme Present 6H No change in expression in surrounding mesenchymal cells.
Specimen 6I: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Pdx1 (assay MGI:7266723).
Structure Level Pattern Image Note
TS23: pancreatic duct Strong 6I Significantly increased expression in ductal cords compared with control.
TS23: pancreas mesenchyme Present 6I No change in expression in surrounding mesenchymal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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