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Gene Expression Data
Assay Details
Assay
Reference: J:132315 Lynn FC, et al., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007 Dec;56(12):2938-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266723
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-Pdx1 polyclonal
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3E: embryonic day 18.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Ppy (assay MGI:7266731).
Structure Cell Type Level Pattern Image Note
TS26: endocrine pancreas type B pancreatic cell Present 3E Expression restricted to beta cells at this stage.
Specimen 3F: embryonic day 18.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Ppy (assay MGI:7266731).
Structure Cell Type Level Pattern Image Note
TS26: endocrine pancreas type B pancreatic cell Weak 3F Expression decreased compared with control.
Specimen 5A: embryonic day 12.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Gcg (assay MGI:7266729).
Structure Cell Type Level Pattern Image Note
TS20: pancreas epithelium progenitor cell of endocrine pancreas Present 5A Expression in undifferentiated pancreatic epithelial progenitors.
Specimen 5B: embryonic day 12.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Gcg (assay MGI:7266729).
Structure Cell Type Level Pattern Image Note
TS20: pancreas epithelium progenitor cell of endocrine pancreas Present 5B No difference compared with control.
Specimen 6A/C: embryonic day 12.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Hes1 (assay MGI:7266737).
Structure Level Pattern Image Note
TS20: pancreas Present 6C , 6A Expression in pancreatic bud.
Specimen 6D/F: embryonic day 12.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Hes1 (assay MGI:7266737).
Structure Level Pattern Image Note
TS20: pancreas Present 6F , 6D No difference compared with control.
Specimen 6G: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Casp3 (assay MGI:7266738).
Structure Level Pattern Image Note
TS23: pancreatic duct Present 6G Expression in ductal cords.
Specimen 6H: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Casp3 (assay MGI:7266738).
Structure Level Pattern Image Note
TS23: pancreatic duct Present 6H Expression in ductal cords.
Specimen 6I: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Casp3 (assay MGI:7266738).
Structure Level Pattern Image Note
TS23: pancreatic duct Present 6I Expression in ductal cords.
Specimen S2A/C: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Mki67 (assay MGI:7266740).
Structure Level Pattern Image Note
TS23: pancreas Present S2C , S2A
Specimen S2D/F: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Pdx1; red - Mki67 (assay MGI:7266740).
Structure Level Pattern Image Note
TS23: pancreas Present S2F , S2D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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