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Gene Expression Data
Assay Details
Assay
Reference: J:316817 Guerra GM, et al., Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis. Cells. 2021 Nov 30;10(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7260272
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Cy3
Assay notes: This antibody recognizes only the cleaved form of the protein.
Results
Specimen S2A Ctr: embryonic day 14.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Single cells S2A Ctr
Specimen S2A CNSdelta: embryonic day 14.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Single cells S2A CNSdelta right , S2A CNSdelta left The number of positive cells has increased significantly in this mutant compared to controls.
Specimen S2C Ctr: embryonic day 14.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS22: ganglionic eminence Present Single cells S2C Ctr left , S2C Ctr right
Specimen S2C CNSdelta: embryonic day 14.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS22: ganglionic eminence Present Single cells S2C CNSdelta left , S2C CNSdelta right The number of positive cells has increased significantly in this mutant compared to controls.
Specimen S2E Ctr: embryonic day 18.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Single cells S2E Ctr
Specimen S2E CNSdelta: embryonic day 18.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Single cells S2E CNSdelta The number of positive cells has increased significantly in this mutant compared to controls.
Specimen S2G Ctr: embryonic day 18.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS26: ganglionic eminence Present Single cells S2G Ctr left , S2G Ctr right
Specimen S2G CNSdelta: embryonic day 18.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:7260275).
Structure Level Pattern Image Note
TS26: ganglionic eminence Present Single cells S2G CNSdelta left , S2G CNSdelta right The number of positive cells has increased significantly in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory